Uh, wow... I just got my genetic testing results from 23andme, its just... a weird feeling. We have tens of thousands of genes that affect who we are, and we still no very little about what they all do (but some we have done a lot of studies on). Im reading this list of things Im likely to be like, tendencies I may have, risks for things that may be higher for me than the general population. Its incredible, but a lot of the data is incomplete. Its still not even legal for 23andme to display health-related data to their customers due to an FDA injunction that is currently barring them from drawing any medical advice from the data (because of how little we actually know about all this). I had to use a third party site that will decode the raw data file that 23andme provides. Some genes have no information - weve identified that this specific gene exists, but we dont really have any information on what it does. Some genes have extensive studies done for them, where they test peoples DNA and then also test them to see if they exhibit some trait to compare the results. So I get stuff like: 2.6x risk of rheumatoid arthritis; 3.10x risk of SLE; 2.28x risk of Sjögrens syndrome; increased risk of type-1 diabetes; and increased risk of primary biliary cirrhosis. poorer metabolizer of several popular medicines; patients prescribed Plavix get less benefit, and have higher risk for adverse cardiovascular events more stimulated by coffee: You appear to have a common genotype in the gene CYP1A2 which metabolizes coffee more slowly than some other forms. The same amount of caffeine will tend to have more stimulating effect on slow metabolizers than on fast metabolizers. Ciprofloxacin is also metabolized by CYP1A2, but is unclear if your genotype should influence its effect. Mix of muscle types. Likely sprinter. Normal for white people. One working and one defective copy of the gene for alpha-actinin-3 in fast-twitch muscle fibres. I also (may?) have a gene called the orchid gene that is associated with a pretty specific personality trait. Theres even an article on that one: theatlantic/magazine/archive/2009/12/the-science-of-success/307761/ Its all just... wow. You should do this. And have everyone in your family do it. At $99 it makes a good holiday present for loved ones (I got it for Kate for our anniversary). Now I understand why Google says we should combine everyones medical information and use data mining techniques to learn more about us. No one wants Google to have their most intimate medical information, but the value for scientific research to be able to look at everyones records at once (and compare it to genetic information) is just too great to ignore. DNA testing is here, and its amazing.
Posted on: Fri, 21 Nov 2014 05:08:07 +0000
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