Albumin Generic name: Albuminar, albutein , buminate, normal human serum Albumin , Plasbumin Dosage/ route 70% to run for q12 x 2 doses Classification Therapeutic: volume expanders Pharmacologic: blood products, colloids. Action Provides colloidal oncotic pressure,which serves to mobilize fluid from extravascular tissues back into the intravascular space. Requires concurrent administration of appropriate crystalloid. Therapeutic effects: increase in intravascular fluid volume. Indication Expansion of plasma volume and maintenance of cardiac output in situations associated with fluid volume deficit,including shock,hemorrhage,and burns. Temporary replacement of Albumin in diseases associated with low levels of plasma protein, such as nephrotic syndrome or end-stage liver disease,resulting in relief or reduction of associated edema. Side effect CNS: headache. CV: pulmonary edema,fluid overload,hypertension,hypotension,tachycardia. GI: increased salivation ,nausea,vomiting. DERM: rash urticaria. MS: back pain. Misc: chills ,fever, flushing. Contraindication Contraindicated in: allergic reactions to albumin; severe anemia;CHF; normal or increased intravascular volume. Used cautiously in: severe hepatic or remake disease; dehydration ( additional fluids may be required); patients requiring sodium restriction; preterm neonates ( infuse slowly due to increased risk of intravascular hemorrhage). Nursing interv. Monitor vital signs ,CVP,and intake and output before and frequently throughout therapy. If fever ,tachycardia,or hypotension occurs,stop infusion and notify physician immediately. Anti histamines may be required to suppress this hypersensitivity response.
Posted on: Sun, 22 Sep 2013 04:54:34 +0000
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