Anti-histone antibodies Anti-histone antibodies are autoantibodies that are found in 50%-70% of patients with systemic lupus erythematosus (SLE) and in more than 95% of patients with drug-induced lupus erythematosus. In other words, a test for anti-histone antibodies has a sensitivity of 50%-70% in detecting patients with SLE and more than 95% sensitivity in detecting patients with drug-induced LE. An ELISA for detecting anti-histone antibodies is said to be positive when there is more than 25 units/ml anti-histone antibodies in a blood sample. 1. eHow 2. Health 3. Conditions & Treatments 4. Immune System Disorders 5. What Is a Histone AB Test? What Is a Histone AB Test? Blood tests are used to determine the presence of histone antibodies Histone AB tests, also known as histone antibody tests, look for proteins in the blood. These histones are materials that bind DNA into cells. Histone AB tests are used to diagnose a number of autoimmune disorders and diseases, including lupus and rheumatoid arthritis. Endocrinologists, rheumatologists and even general practitioners use histone AB tests to help diagnose their patients.
Posted on: Wed, 09 Apr 2014 16:02:53 +0000
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