Ashwagandha (Withania somnifera) Ashwagandha is an herb used in Ayurvedic medicine. Many compounds have been identified from this plant, but activity is most often associated with the withanolides and other steroid lactones. Reported bioactivities include effects on carbohydrate and lipid metabolism, anti-leishmanial activity, immune modulation, decreased anxiety, and prevention of neurodegenerative diseases and cancer. Such an extensive list of possible health benefits for this plant raises the possibility that a more systemic effect could be at work. An examination of the changes in gene, protein, or regulatory RNA expression or localization in response to this herb would help to identify possible explanations for such diverse activity.
Posted on: Tue, 24 Sep 2013 20:31:59 +0000
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