Conclusions In conclusion, intestinal resident immune cells have been shown to display specialized functions aimed at main- taining immune homeostasis. These cells interact and control the reciprocal function of the others. Epithelial cells, in particular, both at steady state and during in- fection sense the external world and relay this infor- mation to underlying immune cells. These interactions can lead either to tolerogenic or to inflammatory immune responses depending on the local status of the intestine. As our knowledge of these players expands, we may understand the contribution of other components like intraepithelial lymphocytes, mast cells, stromal cells, and glial cells in the overall immune homeostasis.
Posted on: Fri, 28 Nov 2014 04:36:35 +0000
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