DNJ (1-deoxynojirimycin) is a component found in mulberry that can fool the body into believing that it is a sugar molecule. By “mimicking” sugar, DNJ binds to the alpha-glucosidase enzyme whose job is to “look” for starches in your intestines to break them down into sugars. When DNJ binds to alpha-glucosidase, the body can’t process as much starch, so this starch (and its calories) passes through the intestine, rather than being absorbed into your blood as sugar. The binding of DNJ to alpha-glucosidase thus allows you to reduce the sugar load in your bloodstream that is created every time you eat a starchy meal. Mulberry inhibits starch-related blood sugar rise in a similar fashion as acarbose, a prescription medication used for blood sugar control. Acarbose helps reduce after-meal blood sugar spikes by inhibiting alpha-glucosidase. Studies demonstrate that mulberry leaf extracts reduce after-meal rises in glucose. Daily use of mulberry leaf extracts can even delay the onset of type II diabetes in experimental models, significantly lowering after-meal insulin and glucose levels and delaying the development of diabetes. The DNJ in mulberry also reduces the production of excess glucose in the liver (gluconeogenesis) as does the anti-diabetic drug metformin. Because around 47% of fasting sugar (after 14 hours of fasting) comes from the liver pumping out glucose, this inhibition can significantly lower the amount of excess glucose circulating in your bloodstream. truemuscle/mulberry-leaf-500mg-piping-rock
Posted on: Mon, 14 Jul 2014 01:40:20 +0000
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