Did You Know: There is Such a Thing as an Endocannabinoid Deficiency??? By Todd Kaighin on Thursday, April 3, 2014 at 1:23pm Education Series : ENDOCANNABINOID DEFICIENCY Edited by : Cannabee Li Source : NORML Did You Know: There is Such a Thing as an Endocannabinoid Deficiency??? CANNABIS BRINGS BALANCE - That Balance is Thought to Achieve Recovery and Maintain Health by those who support Cannabis aka Marijuana Therapies as a Path to Wellness. This one herb and its variety of therapeutic compounds seem to affect every aspect of our bodies and minds. How is this possible? It seems that western medicine is finally catching up with the truth that Ayurvedic Medicine never forgot... But lets start at the beginning... What is the Endocannabinoid System? The endogenous cannabinoid system (ECS); named after the plant that led to its discovery, is perhaps the most important physiologic system involved in establishing and maintaining human health. Endocannabinoids and their receptors are found throughout the body: in the brain, organs, connective tissues, glands, and immune cells. In each tissue, the cannabinoid system performs different tasks, but the goal is always the same: homeostasis, the maintenance of a stable internal environment despite fluctuations in the external environment. As a physician, I am naturally wary of any medicine that purports to cure-all. Panaceas, snake-oil remedies, and expensive fads often come and go, with big claims but little scientific or clinical evidence to support their efficacy. As I explore the therapeutic potential of cannabis, however, I find no lack of evidence. In fact, I find an explosion of scientific research on the therapeutic potential of cannabis, more evidence than one can find on some of the most widely used therapies of conventional medicine. - Dustin Sulak, DO Maine Integrative Healthcare How Our Endocannabinoid System Functions Endocannabinoids and cannabinoids are also found at the intersection of the bodys various systems, allowing communication and coordination between different cell types. At the site of an injury, for example, cannabinoids can be found decreasing the release of activators and sensitizers from the injured tissue, stabilizing the nerve cell to prevent excessive firing, and calming nearby immune cells to prevent release of pro-inflammatory substances. Three different mechanisms of action on three different cell types for a single purpose: minimize the pain and damage caused by the injury. The endocannabinoid system, with its complex actions in our immune system, nervous system, and all of the bodys organs, is literally a bridge between body and mind. By understanding this system we begin to see a mechanism that explains how states of consciousness can promote health or disease. In addition to regulating our internal and cellular homeostasis, cannabinoids influence a persons relationship with the external environment. Socially, the administration of cannabinoids clearly alters human behavior, often promoting sharing, humor, and creativity. By mediating neurogenesis, neuronal plasticity, and learning, cannabinoids may directly influence a persons open-mindedness and ability to move beyond limiting patterns of thought and behavior from past situations. Reformatting these old patterns is an essential part of health in our quickly changing environment. How Do I Regulate My ECS??? Regulating your ECS is as easy as choosing a Cannabis Therapy Regiment suited to your lifestyle and desired results of healing, or health maintenance. There are various ways; aka delivery mechanisms to choose from when planning your Cannabis Therapy - options include INHALE (Breath it In - Vaporizers or Smoking), INGEST (Eating or Drinking) and APPLY (Topical : Salves, Cremes, Lotions, Oils etc.) It gets a little complicated when you start getting into the nitty gritty of strain choice and determining the exact results... Alternative Healing Consultants assist with this very decision; for those that are new to Cannabis Therapy... BUT that is a topic for future blogs... Detailed Research Studies on the Endocannabinoid System (ECS ) and Various Deficiency Related Ailments and Theories: Q&A : Endocannabinoid System: Di Marzo of Italy 2012 Dr. Vincenzo Di Marzo is a Research Director at the Institute of Bio molecular Chemistry of the National Research Council (ICB-CNR) in Pozzuoli, Naples, Italy, coordinator of the Endocannabinoid Research Group in the Naples region, and an Adjunct Associate Professor in the Department of Pharmacology and Toxicology at the Medical College of Virginia at Virginia Commonwealth University in Richmond. Clinical Endocannabinoid Deficiency - ncbi.nlm.nih.gov/pubmed/18404144 STUDY CONCLUSION: Migraine, fibromyalgia, IBS and related conditions display common clinical, biochemical and pathophysiological patterns that suggest an underlying clinical endocannabinoid deficiency that may be suitably treated with cannabinoid medicines. The Endocannabinoid System (ECS) is dysregulated in Multiple Sclerosis (MS) - Cannabis and MS - The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis -- Centonze et al., 10.1093/brain/awm160 -- Brain The ability of cannabinoids to modulate both inflammatory and degenerative neuronal damage prompted investigations on the potential benefits of such compounds in multiple sclerosis (MS) Cannabinoids inhibit neurodegeneration in models of Multiple Sclerosis (MS) - Cannabinoids inhibit neurodegeneration in models of multiple sclerosis -- Pryce et al. 126 (10): 2191 -- Brain Migraine may be related to under production of cannabinoids illinoisnorml.org/index2....o_pdf=1&id=755
Posted on: Wed, 03 Sep 2014 11:59:24 +0000
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