Dr. Teepu Siddique (Northwestern University) discovered the first gene mutation for Amyotrophic Lateral Sclerosis (Lou Gehrig’s disease). This was published in Nature (March 1993). Dr. Siddique used our family’s genealogy, and history of familial ALS in this historic discovery of this first gene. Members of our family carry the SOD1 (G93A) mutation. I have ALS. I have been using many different compounds since the onset of symptoms in an attempt to slow or stop the diseases progress. I have found a combination of organic substances that in my experience have slowed the diseases progress. What I have seen in terms of results from the use of these compounds is significant. I was losing the mobility in my legs, and arms. I began using this compound; within a week I regained mobility in my legs. In several more weeks, I experienced better functioning in my arms, followed by more dexterity in my hands. I am still symptomatic. But the usual progress of ALS in my family has finely shifted, in a positive way for me. Over the last two years I have been working with a person with short term memory loss, that has Alzheimer’s in his family. He also has had a reversal in his disease. Dr. Siddiques recent discovery focuss on a protein-ubiquilin2-. This protein recycles other damaged proteins in the neurons of the spinal cord and the brain in people with ALS. However ubiquilin 2 isn’t doing its job, and the damaged proteins accumulate, leading to paralysis and death. This find offers hope to the 350,000 people worldwide that suffer from ALS and ALS/dementia. What’s more it may one day also treat Alzheimer’s and Parkinson’s disease. Due to our family history with Dr. Siddique, (Professor of Neurology and Cell and Molecular Biology; Director, Neuromuscular Disorders Program) we have discussed these compounds along with several compounds he has found. The outcome was to proceed with specific clinical trials. Dr Siddique will use a genetically altered, mouse model for ALS using these compounds. The purpose is to find a compound that stops ALS. Dr. Siddique was an advisor on the making of the only drug for ALS (Rilutek) and the model was G93A. We are looking for Investors to start a Pharmaceutical Company. Charlie Breidenfield cd4harris@aol 707-694-6393
Posted on: Sun, 17 Aug 2014 01:08:58 +0000
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