Four new grants show local charity support for ISTMs research - TopicsExpress



          

Four new grants show local charity support for ISTMs research Members of the Research Institute for Science & Technology in Medicine led all four successful awards made by the Guy Hilton Research Funding Competition, supported by the Guy Hilton Asthma Trust and University Hospital of North Midlands (UHNM) Charitable Funds. The scheme enabled investigators to submit research projects up to a value of £30,000. There were 14 high quality applications for funding from a range of specialities. The following projects were successful in gaining funding: 1. Professor Christine Roffe and Dr Fahmy Hanna: The relative effectiveness of bolus versus continuous nasogastric feeding after stroke: a proof of principle study. Very little is known about intermittent (bolus) feeding in patients with acute stroke. The overall aim is to determine whether intermittent feeding reduces vomiting and pneumonia, improves nutritional outcomes and leads to faster recovery than continuous feeding. 2. Dr Ed Chadwick: Validation of Structured Light Plethysmography (SLP) in Acute Viral Bronchiolitis. Based on the experience of Dr Chadwicks current study in asthma, the aim is to investigate the potential use of SLP in other conditions, and to optimise data quality from the device. It is therefore proposed to study infants with acute viral bronchiolitis (AVB). 3. Dr Pensee Wu: Prediction of Diabetes in women with Polycystic Ovary Syndrome using an epigenetic approach (PD-PCOS). To identify an epigenetic signature that predicts type-2 diabetes mellitus (T2DM) in PCOS patients. Toward this goal and in the short-term, the project will identify a signature that discriminates PCOS women with T2DM from PCOS women without T2DM. 4. Dr Nick Forsyth: Exploring the role of stem cell strategies for the treatment of chronic asthma. To identify the amenability of the asthmatic respiratory epithelium to MSC-driven (mesenchymal stem cells) reversion of remodelling and immunomodulation. This will be achieved, using in-vitro models, where Dr Forsyths team will explore the utility of the MSC secretome in abrogating IgE and Type 2 cytokine driven immune responses and in reversing airway remodelling. This project was also co-funded by two generous private donations. The next call for proposals for the Guy Hilton Research Funding Competition will be in autumn 2015. The photograph shows the Principal Investigators, clockwise from top left, Professor Roffe, Dr Chadwick, Dr Wu and Dr Forsyth.
Posted on: Mon, 19 Jan 2015 09:24:10 +0000

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