Functional ovarian cysts occurred less frequently in women on higher dose oral contraception.[391] This protection is reduced with the current lower dose products to the point where little effect can be measured.[390, 392, 393, 394, 395] Thus, the risk of such cysts is not eliminated; and, therefore, clinicians can encounter such cysts in patients taking any of the oral contraceptive formulations. 390. Holt VL, Cushing-Haugen KL, Daling JR, Oral contraceptives, tubal sterilization, and functional ovarian cyst risk, Obstet Gynecol 102:252, 2003. 391 Vessey M, Metcalfe A, Wells C, McPherson K, Westhoff C, Yeates C, Ovarian neoplasms, functional ovarian cysts, and oral contraceptives, Br Med J 294:1518, 1987. 392. Lanes SF, Birmann B, Walker AM, Singer S, Oral contraceptive type and functional ovarian cysts, Am J Obstet Gynecol 166:956, 1992. 393. Holt VL, Daling JR, McKnight B, Moore D, Stergachis A, Weiss NS, Functional ovarian cysts in relation to the use of monophasic and triphasic oral contraceptives, Obstet Gynecol 79:529, 1992. 394. Young RL, Snabes MC, Frank ML, Reilly M, A randomized, double-blind, placebo-controlled comparison of the impact of low-dose and triphasic oral contaceptives on follicular development, Am J Obstet Gynecol 167:678, 1992. 395. Grimes DA, Godwin AJ, Rubin A, Smith JA, Lacarra M, Ovulation and follicular development associated with three low-dose oral contraceptives: a randomized controlled trial, Obstet Gynecol 83:29, 1994
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