IN A SLEEPING BRAIN THE WAISTE WAS CLEARED UP TWO TIMES FASTER! - TopicsExpress

IN A SLEEPING BRAIN THE WAISTE WAS CLEARED UP TWO TIMES FASTER! Dr. Nedergaard proposed a brain is equivalent of the lymphatic system, a network of channels that cleared out toxins with watery cerebrospinal fluid. She called it the glymphatic system, a nod to its dependence on glial cells that function as a sort of parallel lymphatic system. With advanced microscopes and dyeing techniques, her team discovered that the brain’s interstitial space — the fluid-filled area between tissue cells that takes up about 20 percent (in humans) of the brain’s total volume — was mainly dedicated to physically removing the cells’ daily waste. When the mice slept, the 14% of its interstitial fluid swelled to over 20 percent. As a result, the cerebrospinal fluid could not only flow more freely but it could also reach further into the brain. In an awake brain, it would flow only along the brain’s surface. Indeed, the awake flow was a mere 5 percent of the sleep flow. nytimes/2014/01/12/opinion/sunday/goodnight-sleep-clean.html?_r=1

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