Jump to: navigation, search Page semi-protected Hepatitis C Classification and external resources Electron micrograph of hepatitis C virus purified from cell culture (scale = 50 nanometers) ICD-10 B17.1, B18.2 ICD-9 070.70,070.4, 070.5 OMIM 609532 DiseasesDB 5783 MedlinePlus 000284 eMedicine med/993 ped/979 MeSH D006526 Hepatitis C is an infectious disease affecting primarily the liver, caused by the hepatitis C virus (HCV).[1] The infection is often asymptomatic, but chronic infection can lead to scarring of the liver and ultimately to cirrhosis, which is generally apparent after many years. In some cases, those with cirrhosis will go on to develop liver failure, liver cancer or life-threatening esophageal and gastric varices.[1] HCV is spread primarily by blood-to-blood contact associated with intravenous drug use, poorly sterilized medical equipment and transfusions. An estimated 130–200 million people worldwide are infected with hepatitis C.[2] The existence of hepatitis C (originally "non-A non-B hepatitis") was postulated in the 1970s and proven in 1989.[3] Hepatitis C only infects humans and chimpanzees.[4] The virus persists in the liver in about 85% of those infected. This persistent infection can be treated with medication: the standard therapy is a combination of peginterferon and ribavirin, with either boceprevir or telaprevir added in some cases. Overall, 50–80% of people treated are cured. Those who develop cirrhosis or liver cancer may require a liver transplant. Hepatitis C is the leading cause of liver transplantation, though the virus usually recurs after transplantation.[5] No vaccine against hepatitis C is available
Posted on: Thu, 27 Jun 2013 21:46:03 +0000
Trending Topics
Recently Viewed Topics
© 2015