One of the amazing, life extending medications for people with Cystic Fibrosis is called Pulmozyme or Dornase Alpha. Heres how it works.... Pulmozyme uniquely targets extracellular DNA to help keep mucus thin and loose. You may know DNA as the code used to build the cells in the body. So you might be wondering how DNA can be a problem for mucus in the lungs. Because of CF, bacteria can build up in extra thick mucus. After white blood cells fight the bacteria, they leave behind extracellular DNA that can make mucus more thick and sticky. Cutting up the extracellular DNA can help thin mucus. Understanding how a pair of scissors can be used to cut something into smaller pieces can help show how Pulmozyme works. Laboratory studies have shown that Pulmozyme cuts apart extracellular DNA to help thin mucus by acting like an enzyme* found naturally in the body. By cutting up the extracellular DNA, Pulmozyme uniquely works to help keep mucus thin and loose. *Enzymes are proteins created by the body to help speed up chemical reactions (such as the breakdown of molecules).
Posted on: Wed, 28 May 2014 16:30:10 +0000
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