QUIZ: A 23-year-old, previously healthy man of Italian - TopicsExpress

QUIZ: A 23-year-old, previously healthy man of Italian origin develops moderate to severe hemolytic anemia. The previous evening he had celebrated a Saint’s day with a feast of beans and pasta. Urinalysis shows free hemoglobin, and the direct Coombs test is negative. Supravital staining of the blood smear demonstrates numerous membrane-bound inclusions (Heinz bodies) within erythrocytes. Which of the following is the most likely diagnosis? (A) G6PD defi ciency (B) Paroxysmal nocturnal hemoglobinuria (C) Sickle cell anemia (D) β-Thalassemia minor (E) Warm antibody autoimmune hemolytic anemia

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