Rheumatology: Systemic Lupus Erythematodes (SLE) Key Info? - TopicsExpress

Rheumatology: Systemic Lupus Erythematodes (SLE) Key Info? Mostly black women are affected. Serous tissues are inflamed Physical Exam Findings? Polyserositis, pleuritis, pericarditis, ascites. Skin shows butterfly rash (malar rash) over the bridge of the nose. Photosensitivity. Symmetrical proximal polyarthritis, Possible glomerulonephritis. Evaluation? You must get a kidney biopsy before you can treat, because of the GN. ANA, ds-DNA, Anti-Sm. Check the Creatinine Clearance. Treatment? Steroids for severe systemic problems. Hydroxychloroquine for the rash and arthritis. Cyclophosphamide for RPGN. NSAIDs for joint pain.

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