These results suggest that downregulation of endocannabinoid (eCB) - TopicsExpress

These results suggest that downregulation of endocannabinoid (eCB) signaling in the nucleus accumbens occurs after chronic unpredictable stress and contributes to the pathophysiology of depression...enhanced CB1 receptor activation can compensate for the deficiency in eCB signaling and therefore ‘normalize mood and emotion. ncbi.nlm.nih.gov/pmc/articles/PMC3055309/ thctotalhealthcare/category/depression-2/

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