Useful information for heart disease patients with diabetes Mild heart disease ( non obstructive CAD) also having increased death risk in diabetic patients - new study CHICAGO — For patients with diabetes, even mild coronary artery disease can increase the risk for death, according to new research from the CONFIRM Registry. CONFIRM involved 34,000 patients from 17 centers in nine countries, 12,086 of whom had follow-up of at least five years. The CONFIRM Registry is an all-comers, real-world prospective registry, said researcher Jonathon Leipsic, MD, from the University of British Columbia in Vancouver, Canada. This study was not interventional; rather, what we are trying to do is learn how to guide prognosis, he explained. Philipp Blanke, MD, also from the University of British Columbia, presented an analysis of data from the registry here at the Radiological Society of North America 100th Annual Meeting. An interesting finding from our study was that patients with mild disease had a very similar prognosis to patients with one-vessel disease, said Dr Blanke. The researchers identified 1823 patients who had diabetes, three-quarters of whom had evidence of coronary artery disease on CT angiography. After more than five years of follow-up, 246 (13.5%) of the patients with diabetes had died. The more coronary vessels exhibiting obstructive coronary disease, the greater the risk for death. Patients with diabetes who did not have evidence of coronary disease had a relatively low death rate. Patients with 1% to 49% stenosis were considered to have mild coronary disease, and those with at least 50% stenosis were considered to have obstructive disease. A risk-adjusted analysis found that both conditions were associated with an increased risk for death. The prognosis of patients with mild disease was similar to that of patients with single-vessel obstructive disease. Table. Mortality Risk for Patients With Diabetes Coronary Artery Disease SeverityHazard Ratio95% Confidence IntervalP ValueMild2.01.3–3.1.003Obstructive2.11.4–3.2
Posted on: Thu, 04 Dec 2014 12:51:30 +0000
Trending Topics
Recently Viewed Topics
© 2015