We invite applications for a PhD position in the research group of Dr. Sonja Lorenz at the Rudolf Virchow Center for Experimental Biomedicine, University of Würzburg, Germany. The successful applicant will have the opportunity to enroll in the ‘Graduate School of Life Sciences’ in Würzburg – a highly-regarded international graduate program funded by the German Excellence Initiative. The PhD position is funded by the Emmy Noether Program of the German Research Foundation (DFG) to explore the molecular mechanisms of ubiquitination and its crosstalk with other types of posttranslational modifications. Available projects aim to uncover how ubiquitination enzymes are regulated on a structural and functional level. The lab combines structural biology (X-ray crystallography, NMR spectroscopy) with biophysical, biochemical and cell biological analyses. Depending on individual qualifications and interests, the successful applicant will have the opportunity to gain experience in various aspects of this multidisciplinary approach. The Lorenz lab has access to state-of-the-art instrumentation in high-field solution NMR spectroscopy, X-ray crystallography, biophysics, and an extensive range of modern biochemical, and cell biological equipment. The Rudolf Virchow Center is integrated into a stimulating, collaborative research environment that includes the Biocenter, the Research Center for Infectious Diseases, various institutes of the university hospital, and the Max Planck Research Group for Systems Biology in Würzburg. Applicants should have a M.Sc./diploma in molecular biology, biochemistry, biophysics, or a related discipline and a strong interest in enzymatic mechanisms and structure-function studies on proteins. Experience in molecular and cell biological techniques is desirable. Additional skills in protein biochemistry or structural techniques, particularly NMR, would be beneficial. Good English language skills are essential; knowledge of German is not required. The position will start on 1 October 2014 or later, upon mutual agreement, and is initially available for 3 years. Salary will be according to the German TVL scale. In case of equivalent qualifications, disabled applicants will be preferentially considered. Applications and informal queries should be sent to Sonja Lorenz by email ([email protected]). Applications are expected to include a letter of motivation detailing research interests and expertise, a CV, and the contact information for at least two references. Review of applications will begin immediately. Lab homepage: virchow.uni-wuerzburg.de/lab_pages/slorenz Institute homepage: rudolf-virchow-zentrum.de/en/research/research-groups/lorenz-group/research.html Website of the Graduate School of Life Sciences: graduateschools.uni-wuerzburg.de/life_sciences
Posted on: Fri, 29 Aug 2014 11:05:45 +0000
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