回ー位宫颈癌患者佳音... 希望帮的到你, - TopicsExpress

回ー位宫颈癌患者佳音... 希望帮的到你, 也祝愿您早日康復! 探讨...白藜芦醇(Resveratrol)对宫颈癌(cervical cancer) 目的： 探讨白藜芦醇(Res)对宫颈癌C33A，SiHa和HeLa细胞增殖与凋亡 的影响. 白藜芦醇（Resveratrol, Res）是广泛存在于葡萄、果类、虎杖等多种食物、药用植物中的一种多酚类化合物. 研究表明，Res具有广泛的预防和抗肿瘤作用，它对白血病、乳腺癌、卵巢癌、肝癌、结肠癌、鼻咽癌、喉癌、甲状腺癌等多种癌瘤细胞具有明显的抑制作用［1-6］. 但目前对Res抑制宫颈癌的研究还远未深入. 宫颈癌(cervical cancer)是最常见的女性生殖道肿瘤，高居发展中国家女性肿瘤发病率的首位. 研究发现，宫颈癌的发生与人乳头瘤病毒（human papilloma virus HPV）感染密切相关，本实验选择3种宫颈癌细胞株，即宫颈腺癌细胞株HeLa、宫颈鳞癌细胞株SiHa和C33A，其中HeLa和SiHa为 HPV阳性的细胞株，C33A为HPV阴性的细胞株. 研究Res对人宫颈癌细胞株的增殖与凋亡的影响，旨在探讨Res对宫颈癌潜在的治疗作用. Resveratrol,对人宫颈癌C33A，SiHa和HeLa细胞的生长抑制作用Res在50 μmol/L以下对宫颈癌细胞的生长无统计学影响，Res在100~600 μmol/L浓度范围内，以浓度和时间依赖的方式抑制宫颈癌C33A细胞的生长（P

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