Answer to yesterday’s quiz: A mean systemic arterial pressure at or above which one of the following thresholds is currently recommended by the guidelines of the Surviving Sepsis Campaign? A. 55 mm Hg. B. 65 mm Hg. C. 75 mm Hg. D. 85 mm Hg. The answer is B. The guidelines of the Surviving Sepsis Campaign recommend initial resuscitation with vasopressors to reverse hypotension, with a mean arterial pressure target of at least 65 mm Hg (grade 1C, indicating a strong recommendation with a low level of evidence). This recommendation is based on the findings of small studies, which showed no significant differences in lactate levels or regional blood flow when the mean arterial pressure was elevated to more than 65 mm Hg in patients with septic shock. nej.md/1mDUeyK
Posted on: Tue, 29 Apr 2014 14:00:00 +0000