Awesome video showing the Sonic Hedgehog signaling pathway in - TopicsExpress

Awesome video showing the Sonic Hedgehog signaling pathway in action. Sonic Hedgehog from outside the cell (pink and white molecule) binds to Patched. (Green receptor) which then allows Smothened (yellow Receptor) into the cilium, which in turn binds with several other proteins that can then enter the nucleus to activiate DNA sequences to tell the cell what to become or where to go. this pathway is responsible for patterning front to back, brain development, facial patterning, and limb patterning. its truly amazing to think of all that happens below the cellular level to create life.

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