* Ciprofloxacin inhibits DNA gyrase. * Rifampicin inhibits RNA - TopicsExpress

* Ciprofloxacin inhibits DNA gyrase. * Rifampicin inhibits RNA polymerase. * Trimethoprim and sulphonamides interfere with bacterial tetrahydrofolate production. * Macrolides, like aminoglycosides, inhibit bacterial protein synthesis. * Penicillins and other beta-lactams interfere with cell wall (peptidoglycan) synthesis. * Remember that glycopeptides are unable to penetrate the outer membrane of Gram-negative bacteria. * Mycoplasma lacks a cell wall and is therefore resistant to beta-lactams.

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