Clozapine is an atypical antipsychotic medication used in the treatment of schizophrenia, and is also sometimes used off-label for the treatment of bipolar disorder. it was first introduced in Europe in 1971, but was voluntarily withdrawn by the manufacturer in 1975 after it was shown to cause #agranulocytosis,. In 1989 after studies demonstrated that it was effective in treating treatment-resistant schizophrenia the United States Food and Drug Administration (FDA) approved the use of clozapine solely for that use, requiring regular white blood cell and absolute neutrophil counts.
Posted on: Sun, 14 Sep 2014 06:48:17 +0000
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