Its better, cognitive decline only. Good for type 1 - TopicsExpress



          

Its better, cognitive decline only. Good for type 1 personality ______________________ Midlife Hypertension Linked to Steeper Cognitive Decline Pauline Anderson August 06, 2014 Elevated systolic blood pressure (SBP) in midlife, but not in late-life, was associated with greater cognitive decline, new research suggests. The results of the new study, conducted by investigators at Johns Hopkins University School of Medicine in Baltimore, Maryland, adds further evidence supporting an association between elevated blood pressure in middle age and cognitive change over time. Midlife hypertension, by several definitions, and elevated midlife but not late-life SBP were associated with more cognitive decline during the 20-year ARIC [Atherosclerosis Risk in Communities] Study. Greater linear decline is found with higher midlife BP in white than in African-American participants, the authors, led by Rebecca Gottesman, MD, PhD, write. The study was published online August 4 in JAMA Neurology. No J Curve For the study, researchers analyzed data on 13,476 middle-aged (48 to 67 years) white and African Americans who were participants in the ARIC study, a prospective epidemiologic study carried out in 4 US communities. Study participants underwent cognitive tests at visit 2 (1990 to 1992), visit 4 (1996 to 1998), and visit 5 (2011 to 2013). They completed 3 cognitive tests: the Delayed Word Recall Test, which assesses verbal learning and short-term memory; the Digit Symbol Substitution Test (DSST), which evaluates executive function and processing speed; and the Word Fluency Test (WFT), which measures executive function and expressive language. Researchers calculated mean Z scores for each cognitive test and developed a global cognitive Z score. They also rigorously measured SBP and diastolic blood pressure (DBP). They defined blood pressure as normal (SBP/DBP
Posted on: Tue, 12 Aug 2014 06:33:04 +0000

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