A 56-year-old woman is diagnosed with metastatic melanoma. - TopicsExpress

A 56-year-old woman is diagnosed with metastatic melanoma. Treatment is begun with an in vitro culture of peripheral leukocytes in the presence of TH1 cytokines, followed by reinfusion into the circulation. After 2 years of remission, the patient returns to the physician for a follow-up examination. A CT scan of the chest shows renewed tumor growth in both lungs. Treatment with the previous therapy is repeated, however, it has no effect on tumor size. Which of the following has most likely been lost from the surface of the tumor cells? A. CD3 B. CD4 C. CD8 D. HLA A, B, and C E. HLA DP, DQ, and DR

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