ARBUTIN NATURAL SKIN LIGHTENING We evaluated skin-lightening effects by clinical study involving 60-human volunteers. The cream containing 1.0 % α-Arbutin lightened the color of the skin and it shows better skin-lightening efficacy than the competitive ingredients, such as Arbutin, Kojic acid and Hydroquinone within a short time, 1 month. Effects of α-Arbutin were sustained during the study period, three months. (Methods) Study subject : 20 persons / group Treatment : treated twice daily with test cream containing 1 % active ingredient Evaluation : objectively by colorimetry at M0 and M1 We examined the inhibitory effect of α-Arbutin toward pigmentation induced by ultraviolet irradiation. As compared with a control cream preparation, a cream preparation containing 2.0 % α-Arbutin had a significant degree of ability to suppress pigmentation induced by ultraviolet irradiation, in the same manner as a cream preparation containing 3.0 % sodium ascorbyl phosphate. It was also confirmed that a cream preparation containing 1.0 % α-Arbutin had a tendency to suppress melanogenesis induced by ultraviolet irradiation, although this effect was weak as compared with that of the cream preparation containing 2.0 % α-Arbutin and the cream preparation containing 3.0 % sodium ascorbyl phosphate. (Methods) Study subject : 23 persons Treatment : treated twice daily with test cream preparations UV-irradiation : one time (the first day of the test) Evaluation : objectively by colorimetry before (week 0) and at weeks 1, 2, and 3.
Posted on: Fri, 21 Jun 2013 01:44:01 +0000