Dear Family and Friends, A good friends daughter is suffering from a rare decease called Friedreichs Ataxia. Friedreichs ataxia is an autosomal recessive inherited disease that causes progressive damage to the nervous system. It manifests in initial symptoms of poor coordination such as gait disturbance; it can also lead to scoliosis, heart disease and diabetes, but does not appreciably affect cognitive function. The disease progresses until a wheelchair is required for mobility. Its incidence in the general population is roughly 1 in 50,000. The particular genetic mutation (expansion of an intronic GAA triplet repeat in the FXN gene} leads to reduced expression of the mitochondrial protein frataxin. Over time this deficiency causes the aforementioned damage, as well as frequent fatigue due to effects on cellular metabolism. The ataxia of Friedreichs ataxia results from the degeneration of nerve tissue in the spinal cord, in particular sensory neurons essential (through connections with the cerebellum) for directing muscle movement of the arms and legs. The spinal cord becomes thinner and nerve cells lose some of their myelin sheath (the insulating covering on some nerve cells that helps conduct nerve impulses). In her journey with this decease, she is trying to raise funds to help find a cure and I asked all of you to encourage at least ten of your friends to take the challenge to donate to help find a cure. Please re-post and select ten of your friends and encourage to take the challenge to help find a cure. Thank you for your good hearts. God Bless us all!! I challenge Johnny P Santander, Nicolas Santander, Ram Chinnachamy, Joyce Surovik Fleetwood, Joan Wiggs, Larry Silcox, OliveBobby Torres, Juvy Banawis Bello- Binag, Noel Cunanan, Ian Francis Sapigao Garcia, Tess Sapigao-Garcia, Nilda Caguioa Cantos, Nikka Viktoria Caguioa Cantos, Mary Gore, Marlene Lebel and Paul Reece Please click on the link below if you want to read more and to donate. God Bless!! tinyurl/lqdm3vm
Posted on: Sat, 13 Sep 2014 15:43:39 +0000
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