Dr. Mahmood Classification of diarrhea by pathophysiologic mechanism Osmotic diarrhea Mg, SO4, PO4 ingestion Carbohydrate malabsorption Malabsorption-related diarrhea Intraluminal maldigestion (pancreatic exocrine insufficiency from chronic pancreatitis, bacterial overgrowth, liver disease) Mucosal disease (celiac sprue, Whipples disease, infections, scleroderma, ischemia, diabetes, hyperthyroidism, hypoparathyroidism) Bile salt deficiency (cirrhosis, Crohns disease, ileal resection, bacterial overgrowth) Inflammatory diarrhea Inflammatory bowel disease Ulcerative colitis Crohns disease Diverticulitis Infectious diseases Tuberculosis Yersiniosis Cytomegalovirus Herpes simplex virus Ischemic colitis Radiation colitis Neoplasm Colon cancer Lymphoma Secretory diarrhea Bacterial, viral, protozoal infections Exogenous stimulant laxatives Endogenous laxatives (malabsorption of bile salts from ileitis) Hormone-producing tumors (carcinoid, VIPoma, medullary cancer of thyroid, mastocytosis, gastrinoma) Villous adenoma (secretion of potassium) Diarrhea due to abnormal intestinal motility Bowel obstruction or fecal impaction Diabetes, Addisons disease, hyperthyroidism Laxatives Irritable bowel syndrome Parkinsons disease Diarrhea due to decreased absorptive surface Small or large bowel resection Enteroenteric fistulas
Posted on: Mon, 17 Mar 2014 05:30:43 +0000
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