I continue to explore the issue of vaccines in dogs and came across this gem in a veterinary paper: ...a “negative” titer does not always correlate with susceptibility. Antibody is a glycoprotein and does dissipate over time. However, immunologic “memory” (B-lymphocytes) is retained for many years for these 3 diseases [distemper, parvo, adenovirus/hepatitis]. Exposure to virulent virus in a previously vaccinated, antibody negative patient typically results in a rapid anamnestic boost‟ of antibody titer and a protective immune response. Annual or triennial boosters are merely a form of immunologic insurance for these 3 diseases. Most animals dont need it. (Ford, 2011 citing Greene & Schultz, 2006).
Posted on: Sat, 26 Jul 2014 12:26:04 +0000
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