It’s not clear exactly how progesterone might work, but the early evidence of its neuroprotective effects is promising, said Dr. Vassilis Koliatsos, who studies neural injury at Johns Hopkins University School of Medicine and is not involved in this study. In a field that “has been plagued by negative studies” disproving treatment options, he said it is worth pursuing.In 2006, Stein and others published a small study of 100 people that found that administering progesterone to people with traumatic brain injury was safe and may lower the mortality rate after one month. Progesterone is a hormone involved in women’s menstrual cycle.Stein’s 2006 study was conducted with consent of patients or their family. Lead author Dr. David Wright, director of emergency neurosciences at Emory University School of Medicine, said it took at least 4½ hours from the point of injury to obtain consent. But scientists believe that the “secondary cascade” of brain damage can begin immediately after trauma.bostonglobe/lifestyle/health-wellness/2013/06/07/researchers-look-conduct-research-without-consent-brain-injury-study/UsEejnzwAUvpKq2eI8TJRL/story.html
Posted on: Mon, 10 Jun 2013 14:02:24 +0000
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