Microwave-assisted synthesis of optically active N-substituted 2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-ones and -thiazin-3(4H)-ones via Smiles rearrangement Abstract: Optically active N-substituted-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-ones and N-substituted-2-methyl-2H-benzo[b][1,4]thiazin-3(4H)-ones with potential synthetic and pharmacological interest were prepared via Smiles rearrangement using microwave irradiation in one-pot from inexpensive (S)-2-chloropropionic acid. Read this original research and sign up to recevie Research and Reports in Medicinal Chemistry journal here: dovepress/articles.php?article_id=13111
Posted on: Tue, 04 Jun 2013 22:53:10 +0000
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