STRAVA PALEOLITICKÉHO TYPU ÚČINNEJŠIA, AKO „ZDRAVÁ“ REFERENČNÁ STRAVA U OSÔB S METABOLICKÝM SYNDRÓMOM: VÝSLEDKY RANDOMIZOVANEJ KONTROLOVANEJ ŠTÚDIE PALEOLITHIC-TYPE DIET MORE EFFECTIVE THEN „HEALTHY“ REFERENCE DIET IN SUBJECTS WITH METABOLIC SYNDROME: RESULTS OF THE RANDOMISED CONTROLLED STUDY Favourable effects of consuming a Palaeolithic-type diet on characteristics of the metabolic syndrome: a randomized controlled pilot-study. Boers I et al. Lipids Health Dis. 2014 Oct 11;13:160. This is the first controlled study on the influence of a Palaeolithic-type diet in subjects with characteristics of the MetS. Over a two week period we found favourable changes in most characteristics of the MetS: a lowering of BP, a change in lipid spectrum and a tendency to higher insulin sensitivity. Despite efforts to keep bodyweight stable, more weight loss was observed in the Palaeolithic group, which is an important outcome of our study. Nevertheless, favourable effects remained after adding weight loss as a separate fixed effect in a post-hoc analysis. No changes were found in specific inflammation parameters, intestinal permeability and the diurnal cortisol slope, possibly explained by the short duration of the dietary intervention or its constant bodyweight design. Indicators for new insights in the pathophysiological mechanisms underlying the MetS and CVD could possibly be found in the lowering effect on white blood cell count and lower levels of urinary calcium and magnesium. The generalizability of this study might be high, because of the broad inclusion criteria, men and women with diverse combinations and characteristics of the MetS. Our results are in line with results from earlier research in related target groups. Full-text: ncbi.nlm.nih.gov/pmc/articles/PMC4210559/
Posted on: Sat, 17 Jan 2015 09:49:09 +0000
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