Synonyms: G6PD/G-6-PD deficiency, non-spherocytic hemolytic anaemia The enzyme glucose-6-phosphate dehydrogenase (G6PD) is one of the enzymes of the pentose phosphate pathway. This pathway is involved in keeping an adequate amount of the coenzyme nicotinamide adenine dinucleotide phosphate (NADPH) in cells. NADPH in turn maintains the levels of glutathione which protects the red cell from oxidative damage. G6PD is the rate-limiting enzyme in the pentose phosphate pathway. Thus, deficiency of the G6PD enzyme results in reduced glutathione making the red cells vulnerable to oxidative damage and thus liable to hemolysis. #G6PD carrier of the family #my brother and my son also G6PD deficient
Posted on: Sun, 29 Jun 2014 06:36:18 +0000
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