TOTAL 33 MCQs seem CONTROVERSIAL, I am posting with REFERENCES and - TopicsExpress

TOTAL 33 MCQs seem CONTROVERSIAL, I am posting with REFERENCES and REASONING, Thank You Every1 for the help!! 1. Which of the following is adrenergic neurone blocker drug? A. Guanethidine B. Reserpine C. Sodium Nitropruside D. Hydrallazine Ans. A. Guanethidine AND B. Reserpine. Reference: Pharmacology by KD Tripathi 6th edition pg. 133. 2. Receptor concept was first introduced by: A. Walksman B. Paul Ehrlich C. Simmonds D. Langley Ans. B. Paul Ehrlich AND D. Langley Reference: Pharmacology by KD Tripathi 6th edition pg. 41. Competitive antagonism is seen between specific agonists and antagonists. Langley in 1878 was so impressed by the mutual antagonism among two alkaloids pilocarpine and atropine that he proposed that both reacted with the same receptive substance on the cell. Ehrlich (1900) observed quantitative neutralization between toxins and antitoxins and designated receptor to be the anchoring group of the protoplasmic molecule for the administered compound. 3. Which of the following is radiomimetic drug? A. Azathioprine B. Busulfan C. 5-FU D. Nitrogen mustard Ans. B. Busulfan AND D. Nitrogen mustard Reference: Harrison’s Principles of Internal Medicine 18th Edition / Chapter 107. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes. Reference 2: Surgical Pathology of the GI Tract, Liver, Biliary Tract, and Pancreas by Robert D. Odze, John R. Goldblum Chapter 43, pg 1161. Clinical Immunobiology, Volume 1 by Fritz H. Bach, Robert A. Good Pg 91 (For azathioprine). 4. Which of the following is used for treatment of pulmonary hypertension? A. Phospohodiesterase-5 inhibitors B. Beta2 adrenergic agonists C. Calcium channel blockers D. Angiotensin II receptor antagonists Ans. A. Phospohodiesterase-5 inhibitors and C. Calcium channel blockers. (Ref. Harrison’s medicine 18th/ch. 250). Drug Treatment of Pulmonary arterial hypertension CALCIUM CHANNEL BLOCKERS Patients who respond to short-acting vasodilators at the time of cardiac catheterization (a fall in mean pulmonary arterial pressure of 10 mmHg and a final mean pressure Chapter 26. Stomach. 33. Pressure sores occur most commonly in A. Ischium B. Sacrum C. Heel D. Occiput Ans. B. Sacrum (SABISTON TEXTBOOK) Ans. A. Ischium (BAILEY AND LOVE 26th) Sir although Bailey and Love 26th edition has given ischium as most common site, Sabiston Textbook of Surgery has given sacrum the most common site for pressure sore Sabiston Textbook of Surgery page 1948 = “In order of occurrence, the surfaces most commonly involved are those over the sacrum, calcaneus, ischium, and greater trochanter.

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