The MLH1 c.1852_1853delinsGC (p.K618A) Variant in Colorectal - TopicsExpress

The MLH1 c.1852_1853delinsGC (p.K618A) Variant in Colorectal Cancer: Genetic Association Study in 18,723 Individuals conclude this variant in the MLH1 gene should be regarded as a polymorphism without functional effect on the MLH1 protein, no role in genetic predisposition to Lynch syndrome, as well as no apparent effect as a low-penetrance variant for CRC genetic susceptibility. ncbi.nlm.nih.gov/pmc/articles/PMC3990597/

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