This medical presentation is about Staging Prostatic Adenocarcinoma in Radical Prostatectomy Specimins. Pathologic Staging - Is there an approach that allows pathologists to assess histologic staging in RP specimens more efficiently and with more confidence? “Secrets” - 1) Systematic submission of tissue at gross bench. Exact location of submitted tissue in each block. 2) Knowledge of microanatomy, McNeal’s Zonal anatomy, Histologic variation in each zone–Extraprostatic tissue. Entire apex margin + next section, Entire bladder neck margin + next section, At least every other intervening macrosection. The Other Secret: Detailed Block Summary, A1: apical margin (perpendicular), A2: bladder base margin (perpendicular), A3: macrosection 1 near apex, complete, A4: macrosection 3, right half, A5: macrosection 3, left half, A6-7: macrosection 5, right half, A8-9: macrosection 5, left half, A10: macrosection 6, near bladder neck, complete. One can recognize the different anatomic regions by histology. Each individual region has different specific issues with staging. Microscopic Anatomy.
Posted on: Mon, 25 Nov 2013 12:26:51 +0000
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