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NEW JOURNAL STUDIES •Bevacizumab for type 1 ROP may cause lasting abnormalities •OCT-measured drusen load predictive of AMD prognosis •Single diurnal curve in glaucoma patients has limited value •Glaucoma history linked to corneal graft failure •Wireless IOP transducer appears safe NEW JOURNAL STUDIES FROM THE MIDDLE EAST AND AFRICA (MEAJO) •Laser plus anti-VEGF improves BRVO outcomes •Survey outlines major causes of uveitis in Iraq ACADEMY NEWS •AAO Meetings on Demand •Academy costume contact lens warning on national TV •Share your expertise on the new-and-improved EyeWiki •Read this year’s Foundation highlights -------------------------------------------------------------------------------- NEW JOURNAL STUDIES Bevacizumab for type 1 ROP may cause lasting abnormalities Investigators randomized 13 infants with type 1 zone 1 ROP to receive 0.5 mg bevacizumab in one eye, and laser in the fellow eye. Twenty-three eyes completed the study. At nine months, macular abnormalities were still evident in 75% of bevacizumab eyes and in 36.4% of lased eyes, capillary bed loss was noted in more bevacizumab eyes (91.6% vs. 27.3%), as were branching abnormalities (tangles) (91.6% vs. 27.3%). Until more long-term evidence is in, physicians “should err on the side of caution,” the authors conclude. Ophthalmology, November 2014 OCT-measured drusen load predictive of AMD prognosis This retrospective review evaluated whether SD-OCT analysis of drusen load at baseline could predict development of advanced AMD in patients with non-neovascular AMD and no retinal pigment epithelial atrophy at baseline. This is the first study to demonstrate that SD-OCT measurements of drusen load, by area (P = .005) or volume (P = .001), can predict RPE atrophy. Additionally, they confirmed the association between drusen load, by area or volume, and development of advanced AMD. Simple and practical, these measurements have potential in routine clinical care and clinical trials. American Journal of Ophthalmology, October 2014 Single diurnal curve in glaucoma patients has limited value This retrospective review included 92 patients with primary open-angle glaucoma who underwent four diurnal IOP curve measurements six months apart with Goldmann applanation tonometry recorded in the sitting position. They found poor between-visit agreement of IOP values and curve parameters, meaning that IOP does not follow a reproducible diurnal pattern over the long term in untreated patients with glaucoma or those treated with a stable treatment regimen. In patients who underwent filtering surgery, there was only an acceptable between-visit agreement of IOP values and curve parameters. Ophthalmology, October 2014 Glaucoma history linked to corneal graft failure This evaluation of data from the Cornea Donor Study, a large multicenter trial evaluating long-term cornea transplant survival among patients who underwent penetrating keratoplasty, finds that 12% had at least one definite rejection episode and 16% had a probable rejection episode at 10 years. The only significant risk factor for graft rejection was a history of glaucoma, especially among patients who had prior glaucoma surgery and were using glaucoma medications at the time of corneal transplantation. The 10-year incidence of graft rejection was 35% in these patients compared to 14% in eye without a history of glaucoma. Cornea, October 2014 Wireless IOP transducer appears safe Investigators report preliminary safety data for a wireless intraocular pressure transducer implanted in a in a single patient with open-angle glaucoma. Implanted into the ciliary sulcus following extracapsular cataract extraction and in the bag intraocular lens implantation, the transducer is intended to allow for 24-hour IOP monitoring. The device was well-tolerated throughout 18 months of follow-up. JAMA Ophthalmology, October 2014 Back to Top -------------------------------------------------------------------------------- NEW JOURNAL STUDIES FROM THE MIDDLE EAST AND AFRICA (MEAJO) Laser plus anti-VEGF improves BRVO outcomes Investigators randomized 30 patients with macular edema secondary to branch retinal vein occlusion (BRVO) to a single dose of ranibizumab or bevacizumab and grid laser treatment, or grid laser alone. At 6 months, patients in both combined treatment groups had better outcomes than the laser alone group, with 60% of the ranibizumab group and 40% of the bevacizumab group achieving a gain of ≥3 lines of Snellen acuity, compared with only 20% in the laser only group. However, the mean difference in BCVA and central foveal thickness was not statistically significant (P > 0.05) among the three groups. Middle East Africa Journal of Ophthalmology, October 2014 Survey outlines major causes of uveitis in Iraq This prospective case series analyzed all cases of active uveitis seen at a referral center in Baghdad, Iraq over a four-year period. Posterior and panuveitis were the most common types of uveitis. Toxoplasmosis and presumed ocular tuberculosis were the most common infectious causes of uveitis while Vogt-Koyanagi-Harada disease, Behηets disease, and pars planitis were the most common non-infectious causes. Macular degenerations or scars and optic nerve atrophy were the most common causes of irreversible blindness. Middle East Africa Journal of Ophthalmology, October 2014 Back to Top -------------------------------------------------------------------------------- ACADEMY NEWS AAO Meetings on Demand Did you miss a presentations last week in Chicago? AAO Meetings on Demand has captured more than 200 hours of content that took place at AAO 2014 and Subspecialty Day meetings. You can purchase a single Subspecialty Day meeting or all eight Subspecialty Day meetings plus AAO 2014 sessions. AAO Meetings on Demand captures the presenters’ slides, synchronized with audio. View on your iPad, iPhone and Android 2.3 or higher mobile device. AAO Meetings on Demand does not offer CME credit. Academy costume contact lens warning on national TV Good Morning America recently aired a segment warning the public about non-prescription costume contact lenses, featuring Dr. Thomas Steinemann, speaking on behalf of the Academy. It also tells the story of Julian Hamlin, who after 10 surgeries is still recovering from damage caused by over-the-counter colored contact lenses. Find out more about Julian Hamlin’s story and contact lens safety on the Academy’s EyeSmart website. Share your expertise on the new-and-improved EyeWiki EyeWiki is the Academy’s collaborative online encyclopedia where ophthalmologists can read, write and edit articles on eye disease and treatment. The site now has a cleaner, more colorful look and mobile-friendly design that adjusts for any screen size. Behind-the-scenes improvements also make it easier for you to write and edit articles using the latest wiki technology. See the new site and contribute your expertise today at aao.org/eyewiki. Read this year’s Foundation highlights The Academy Foundation’s 2013-14 annual report, Advancing Quality of Eye Care for a Better Quality of Life, illustrates the impact the Foundation made this year, including a $1 million gift to establish a new pediatric ophthalmology education center on the ONE Network, progress on the landmark IRIS™ Registry, and the continuing good work of EyeCare America® and the International Outreach Program. Your support enables these programs to continue to innovate and inspire. Back to Top -------------------------------------------------------------------------------- MIDDLE EAST AND AFRICA ADVISORY PANEL: Middle East African Council of Ophthalmology (MEACO): Drs.Mansur Rabiu, Deepak Edward Egyptian Ophthalomological Society (EOS): Dr. Ahmed Mostafa Ismail Ophthalmological Society of Ethiopia (OSE): Drs. Alemayehu Weldayes, Dereje Nigussu Ophthalmological Society of Ghana (OSG): Dr. Stephen Akafo Iranian Ophthalmological Society (IRSO): Drs. Mohammad Mehdi Parvaresh, Masoud Soheilian, Alireza Lashay Iraqi Ophthalmological Society (IOS): Dr. Hamzah Al-Majedi Ophthalmological Society of Nigeria (OSN): Dr. E. O. Babalola Oman Ophthalmic Society (OOS): Drs. Rashid Al Saidi, Anuradha Ganesh Palestinian Ophthalmological Society (POS): Dr. Maged A. Abu-Ramadan Syrian Ophthalmological Society (SOS): Dr. Anas Anbari Turkish Republics Ophthalmology Society (TROS): Drs. Sunay Duman, Levent Akcay Uzbek Ophthalmologists Society (UOS): Dr. Nazim Zaynutdinov Yemeni Ophthalmic Society (YOS): Dr. Tawfik Al-Khatib Editor-in-Chief: Dr. David W. Parke II Chief Medical Editor: Dr. Philip R. Rizzuto Managing Editor: Susanne Medeiros AAO Advisory Panel: Drs. Terry L. Forrest, Jean E. Ramsey, Milam A. Brantley, James C. Tsai, Eliza Hoskins, Sunita Radhakrishnan CONTACT INFORMATION Middle East African Council of Ophthalmology (MEACO): [email protected] Egyptian Ophthalomological Society (EOS): eos@eos1902 Ophthalmological Society of Ethiopia (OSE):[email protected] Ophthalmological Society of Ghana (OSG): [email protected] Iranian Ophthalmological Society (IRSO): [email protected] Iraqi Ophthalmological Society (IOS): [email protected] Ophthalmological Society of Nigeria (OSN): osnigeria@yahoo Oman Ophthalmic Society (OOS): eyeoos@gmail Palestinian Ophthalmological Society (POS): [email protected] Syrian Ophthalmological Society (SOS): secretary@sos-sy Turkish Republics Ophthalmology Society (TROS): sunayduman@superonline Uzbek Ophthalmologists Society (UOS): [email protected] Yemeni Ophthalmic Society (YOS): [email protected]
Posted on: Fri, 31 Oct 2014 16:47:33 +0000