Multi-drug sensitivity, also referred to as MDR1, is a genetic mutation that affects breeds such as Collies, Shepherds, Sheep Dogs, Whippets and even some mixed herding breeds. According to the Veterinary Clinical Pharmacology Lab at Washington State University, three-quarters of all Collies and as many as half of all Australian Shepherds in the United States may be affected by the gene. What it means is that a dog is unable to expel certain medications from its system. Unable to be secreted from the system, the medication builds in the brain until it reaches toxic levels. It can lead to severe illness and even death. Thanks Katie George for the great info!!
Posted on: Wed, 24 Jul 2013 22:12:22 +0000
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