Nature Reviews Drug Discovery: Histone deacetylases (HDACs) are a - TopicsExpress

Nature Reviews Drug Discovery: Histone deacetylases (HDACs) are a class of epigenetic enzymes that remove acetyl groups from lysine residues on histones and other proteins. In this Review, Falkenberg & Johnstone highlight the role of HDACs in cancer, neurological diseases and immune disorders, and discuss the development of small-molecule inhibitors. bit.ly/1vU0tCF (£) Nature Reviews Nature Reviews Drug Discovery: Histone deacetylases (HDACs) are a class of epigenetic enzymes that remove acetyl groups from lysine residues on histones and oth...

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