Probably explains too why identical twins can be so different ... copied: One Human, Multiple Genomes scim.ag/1c6KXdQ With recent advances in genome-wide assays, it is becoming increasingly apparent that a human individual is made up of a population of cells, each with its own “personal” genome. Thus, mosaicism is perhaps much more common within multicellular organisms than our limited genomic assays have detected thus far, and may represent the rule rather than the exception. A few base pair changes, a few extra copies of a repetitive sequence— these things seem small on the scale of 3 billion base pairs, but it does mean that there is no “true you” spelled out in your genes, and it also means that these slight differences could impact development and health. Read the Perspective: scim.ag/1c6KXdQ or listen to the FREE podcast: scim.ag/1c6LfRX [Image: P. Huey/Science/Manners of Mosaicism]
Posted on: Fri, 26 Jul 2013 20:11:54 +0000
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