THIS IS FOR ALL THAT DONT UNDERSTAND THE HISTORY OF THESE UNITED STATES, AS I SAID, THERE WAS A BIGGER PLAN IN BRINGING THOSE 2 FOLKS WITH EBOLA TO THE USA...HERES PROOF OF OWNERSHIP... Patents Find prior artDiscuss this application Publication number CA2741523 A1 Publication type Application Application number CA 2741523 PCT number PCT/US2009/062079 Publication date Apr 29, 2010 Filing date Oct 26, 2009 Priority date Oct 24, 2008 Also published as EP2350270A2, 4 More » Inventors Jonathan S. Towner, 4 More » Applicant Jonathan S. Towner, 5 More » Export Citation BiBTeX, EndNote, RefMan Classifications (21) External Links: CIPO, Espacenet Human ebola virus species and compositions and methods thereof CA 2741523 A1 ABSTRACT Compositions and methods including and related to the Ebola Bundibugyo virus (EboBun) are provided. Compositions are provided that are operable as immunogens to elicit and immune response or protection from EboBun challenge in a subject such as a primate. Inventive methods are directed to detection and treatment of EboBun infection. CLAIMS(30) 1. An isolated hEbola virus comprising a nucleic acid molecule comprising a nucleotide sequence of: a) a nucleotide sequence set forth in SEQ ID NOS: 1 or 10; b) a nucleotide sequence hybridizing under stringent conditions to SEQ ID NOS: 1 or 10; or c) a nucleotide sequence of at least 70%-99% identity to the SEQ ID NOS: 1 or 10. 2. An isolated hEbola virus having Centers for Disease Control Deposit Accession No. 200706291. 3. The hEbola virus of any one of claims 1 or 2 which is killed. 4. The hEbola virus of claim 1 which is an attenuated hEbola virus. 5. The virus of claim 4 wherein at least one property of the attenuated hEbola virus is reduced from among infectivity, replication ability, protein synthesis ability, assembling ability or cytopathic effect. 6. An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NOS: 1 or 10 or a complement thereof. 7. An isolated nucleic acid molecule comprising a nucleotide sequence of between 4 and 4900 contiguous nucleotides of the nucleotide sequence of SEQ ID NOS: 1 or 10, or a complement thereof; with the proviso that said nucleotide sequence is not comprised by the nucleotide sequence set forth in SEQ ID NO: 20; or between 5500 and 6600 contiguous nucleotides of the nucleotide sequence of SEQ ID NOS: 1 or 10, or a complement thereof. 8. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence of SEQ ID NO: 2-9, 59, or SEQ ID NO: 11-19 or a complement of said nucleotide sequence. 9. An isolated RNA or DNA nucleic acid molecule which hybridizes under stringent conditions to a nucleic acid molecule having the nucleotide sequence of SEQ ID NOS: 1 or 10 or a complement thereof. 10. An isolated polypeptide encoded by the nucleic acid molecule of any one of claims 7-9. * AND SO ON AND SO FORTH... THE US GOVT OWNS THE EBOLA PATENT...I GUESS MY PTSD WAS GUIDING ME TOWARDS THE TRUTH...
Posted on: Fri, 22 Aug 2014 03:52:32 +0000