ALBERTO LAZARO...PA QUE APRENDAS!!!! Toxicity: Excess manganese interferes with the absorption of dietary iron. Long-term exposure to excess levels may result in iron-deficiency anemia. Increased manganese intake impairs the activity of copper metallo-enzymes. Manganese overload is generally due to industrial pollution. Workers in the manganese processing industry are most at risk. Well water rich in manganese can be the cause of excessive manganese intake and can increase bacterial growth in water. Manganese poisoning has been found among workers in the battery manufacturing industry. Symptoms of toxicity mimic those of Parkinsons disease (tremors, stiff muscles) and excessive manganese intake can cause hypertension in patients older than 40. Significant rises in manganese concentrations have been found in patients with severe hepatitis and posthepatic cirrhosis, in dialysis patients and in patients suffering heart attacks. Laboratory Diagnosis: Manganese influences the copper and iron metabolism and estrogen therapy may raise serum manganese concentration, whereas glucosteroids alter the manganese distribution in the body. Significance of Blood Levels: Mass spectroscopy levels of whole blood reliably reflect the nutritional intake and acute industrial exposure. Note: In the presence of high levels, dopamine levels are reduced. Significance of Urinary Levels: 24-hr urine to evaluate excessive industrial exposure. Significance of Hair Manganese Levels Dark hair dyes can contain manganese and thus falsely elevate hair levels. In the case of extremely high manganese levels obtained from scalp hair, pubic hair should be tested as a control. Manganese overload is generally due to industrial pollution. Workers in the manganese processing industry are most at risk. Water: EPA recommends a level of 0.05PPM in drinking water, based upon taste rather than health. Symptoms of increased manganese levels: Psychiatric illnesses Mental confusion Impaired memory Loss of appetite Mask-like facial expression and monotonous voice Spastic gait Neurological problems Other manifestations include: Impaired thiamin (B1) metabolism Iron deficiency Increased demand for vitamin C and copper. Manganese toxicity can cause kidney failure, hallucinations, as well as diseases of the central nervous system. High hair manganese levels indicate problems with calcium and/or iron metabolism.
Posted on: Thu, 24 Jul 2014 15:27:02 +0000
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