* Allergic Reactions to Anesthetic Agents* True anaphylaxis due to anesthetic agents is rare; anaphylactoid reactions are much more common. Muscle relaxants are the most common cause of anaphylaxis during anesthesia, with an estimated incidence of 1 in 6500 patients. They account for almost 60% of perioperative anaphylactic reactions. rocuronium, succinylcholine, and atracurium were most often responsible Although rarer, hypnotic agents can also be responsible for some allergic reactions. The incidence of anaphylaxis for thiopental and propofol is 1 in 30,000 and 1 in 60,000, respectively. Allergic reactions to etomidate, ketamine, and benzodiazepines are exceedingly rare. .anaphylactic reactions due to opioids are far less common than nonimmune histamine release. anaphylactic reactions to local anesthetics are much less common than vasovagal reactions, toxic reactions to accidental intravenous injections, and side effects from absorbed or intravenously injected epinephrine. IgE-mediated reactions to ester-type local anesthetics, however, are well described secondary to reaction to the metabolite, para-aminobenzoic acid, anaphylaxis due to amide-type local anesthetics is very rare; in some instances, the preservative (paraben or methylparaben) There are no reports of anaphylaxis to volatile anesthetics
Posted on: Sat, 24 Jan 2015 09:56:13 +0000
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