Cute :) The existing target-enrichment strategies, based on - TopicsExpress



          

Cute :) The existing target-enrichment strategies, based on polymerase chain reaction (PCR) , hybridization or molecular inversion probes (15) merely detect variations, without isolation of the intact allele as a clone that can be further analyzed to link polymorphisms over large regions or to be genetically manipulated for downstream functional analysis... ..In this study, we present a simple approach, based on recombineering for targeted isolation of genomic regions in a vector format, suitable for downstream analysis. ncbi.nlm.nih.gov/pmc/articles/PMC3203589/
Posted on: Tue, 24 Sep 2013 17:58:02 +0000

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