High Blood Pressure Caused by Renal Failure High blood pressure and renal failure are a pair of pathological phenomenon. They often co-exist and will interact and worsen each other. Elevated high blood pressure is one common symptom of renal failure and there are mainly two aspects of reasons why renal failure will cause blood pressure to increase. One reason is increased secretion of renin. In case of renal parenchymal or vascular impairments, there will be sharp increase of renin. This will cause small artery spasm and increased artery resistance, thus causing blood pressure to increase. That is why the incidence, duration and severity of high blood pressure are closely related with degree of renal damages and pathological changes. For example, blood pressure can return to normal in case of acute nephritis while high blood pressure is not easy to be lowered in case of chronic nephritis. The other reason is reduced secretion of anti-hypertension substances such as prostaglandin. High blood pressure is one independent factor for worsening renal functions and it is one of the major cause of cardio-cerebrovascular complications. 24-h persistent and effective controlling of high blood pressure plays vital role in protecting the kidneys, slowing down or even reversing renal failure progression. The ideal blood pressure for renal failure patients: Before dialysis(GFR>10ml/min): blood pressure should be below 130/80mmHg On dialysis: blood pressure should be lower than 140/90mmHg Proteinuria>1g/24h: blood pressure should be below 125/75mmHg Proteinuria
Posted on: Fri, 29 Nov 2013 06:10:51 +0000
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