MITIGATION MONDAY ~ UNDERSTANDING THE MULTIPIER EFFECT: Recent insights into the mechanisms underlying the biological effects of low dose effects of ionising radiation have revealed that similar mechanisms can be induced by chemical stressors in the environment. This means that interactions between radiation and chemicals are likely and that the outcomes following mixed exposures to radiation and chemicals may not be predictable for human health, by consideration of single agent effects. Our understanding of the biological effects of low dose exposure has undergone a major paradigm shift. We now possess technologies which can detect very subtle changes in cells due to small exposures to radiation or other pollutants. We also understand much more now about cell communication, systems biology and the need to consider effects of low dose exposure at different hierarchical levels of organisation from molecules up to and including ecosystems. Furthermore we understand, at least in part, some of the mechanisms which drive low dose effects and which perpetuate these not only in the exposed organism but also in its progeny and in certain cases, its kin. This means that previously held views about safe doses or lack of harmful effects cannot be sustained. Journal of Radiological Protection Volume 29 Number 2A Carmel Mothersill and Colin Seymour 2009 J. Radiol. Prot. 29 A21 doi:10.1088/0952-4746/29/2A/S02 iopscience.iop.org/0952-4746/29/2A/S02;jsessionid=593DBF6934C1E7B9A88C66E01071836C.c3%20 One of the BEST explanations ever given for understnding EXACTLY how radiation effects our cells & organ systems: https://youtube/watch?v=meOaJglmO4U
Posted on: Tue, 02 Dec 2014 01:05:01 +0000
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