SBA: A 29-year-old woman who is 39 weeks pregnant presents to the - TopicsExpress

SBA: A 29-year-old woman who is 39 weeks pregnant presents to the delivery suite in labour. Her previous child was affected by group B streptococcus (GBS) infection. She is allergic to penicillin. Which antibiotic should be prescribed for her as a prophylaxis for GBS? A. Ampicillin B. Cephalosporins C. Clindamycin D. Gentamycin E. Metronidazole The answer is Clindamycin. Ampicillin may be used as an alternative to penicillin, however, it should be avoided because it covers a broader spectrum and may be associated with Gram-negative sepsis. Cephalosporins may have 10% cross reactivity with penicillin allergy. Gentamycin is not relevant in this situation. Vancomycin and erythromycin can potentially be used when clindamycin is not recommended.

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