1 gram a day of powder or extract of Ashwagandha Root shown to improve the cognitive and psychomotor performance in healthy human participants, The decrease in the reaction time could be interpreted as a central effect, since Withania somnifera helps to maintain homeostasis and psychomotor abilities in times of stress. Clinical trials have shown that Withania somnifera can alleviate a reactive type of depression without causing sedation. Instead, it optimizes mental and psychomotor performance by easing the mental stress bundle.[8] Our results are in par with the above data where we have not witnessed any sedative effect in the subjects during treatment with Withania somnifera extract. The mechanism by which Withania somnifera exerted beneficial effects is presently not clear; however, animal studies have shown that Withania somnifera is capable of improving memory and enhancing cognitive function by modulation of cholinergic neurotransmission. As per the literature, leaf and fruit extracts of Withania somnifera consisting of mixtures of sitoindosides VII-X and withaferin-A produces an increase in the cortical muscarinic acetylcholine capacity, which may partly explain cognition-enhancing effect demonstrated in animal and human models. ncbi.nlm.nih.gov/pmc/articles/PMC3897003/
Posted on: Sun, 28 Dec 2014 20:02:13 +0000
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