Influenza viruses A & B Influenza A is more virulent and common than influenza B, but both have been linked to epidemics and pose threats to those hospitalized, especially young or elderly. Influenza A is an avian virus that has migrated to humans while Influenza B only affects humans, which are reservoirs for both. Influenza viruses are round or filamentous and have an RNA (single-strand) genome, which is in 8 segments inside a protein envelope. The segmented genome allows for new strains to develop easily and quickly, making vaccines short-lived. The virus binds to the host cell, allowing entry of the RNA into the host. The genes are copied and the host cell begins producing viral particles. Influenza viruses stimulate the antibody-mediated immune response. Influenza infections usually present as fever, chills, myalgia, and cough but can progress to viral pneumonia and secondary bacterial pneumonia. Transmission is by droplet particles directly to mucous membranes or by infected hands making contact with mucous membranes. Infection Control Committee
Posted on: Tue, 15 Jul 2014 06:52:05 +0000
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