Methotrexate is a folate antagonist. It inhibits enzymes required - TopicsExpress

Methotrexate is a folate antagonist. It inhibits enzymes required for DNA base synthesis. To prevent harm to normal cells, a fully activated form of folic acid known as leucovorin (folinic acid; citrovorum factor) can be administered. Administration of leucovorin is known as: a. Induction therapy. b. Consolidation therapy. c. Pulse therapy. d. Rescue therapy. answer at no. 20 of : rnpedia/home/exams/nclex-exam/nclex-sample-questions-for-pharmacology-2/answer-and-rationale

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